Overview of Chosen Chemical Compounds and Intermediates
Overview of Chosen Chemical Compounds and Intermediates
Blog Article
1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected with bortezomib, a proteasome inhibitor Utilized in the cure of various myeloma. Its synthesis or analyze is important for guaranteeing the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the therapy of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound during the synthesis of imatinib, a drug that targets certain varieties of cancer, like Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their analyze is very important for optimizing the generation procedure and making sure superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is made use of to treat breast most cancers, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Utilized in the procedure of breast cancer. Several intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers including ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of 5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde colorectal most cancers and small cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have different apps, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of assorted gluconic acid derivatives, that are Utilized in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to handle kind tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 2 diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).